KMID : 0378019740170101350
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New Medical Journal 1974 Volume.17 No. 10 p.1350 ~ p.1360
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Studies on the phenylketonuria in Korean, primary school pupils
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Abstract
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Plasma phenylalanine measurement of primary school pupils, amounts to 19,726 presumably esti¡þmated, in Korean have performed by the fluorometric method. Mean values of plasma phenylalanine concentration are 0.98 ¡¾0.47 mg/100 ml by arithmatic, and are 0.92¡¾0.42 mg/100 ml, 0.90¡¾0.38 mg/ 100 ml in males and 0.93¡¾0.42 mg/100ml in females by means of probability graph method. Values of males are slightly lower than those of females. The pupils having 2 mg/100 ml or more have had within normal limits in point of hematologic and urinary findings. Three of those have taken phenylalanine tolerance test, in which they appeared as normal disappearance of phenylalanine from blood as control group. In point of rate constants, however, one of three, case of Lee, appeared as a variant of phenylketonuria as described in Woolf et al. 60.51) Case of Lee showed that rate constant were progressively increeased with time but other 2 cases showed reverse tendency, progressively decreased.
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KEYWORD
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